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iBioS successfully combines the excellence of two renowned institutes:

iBioS is part of the research network BioQuant

About iBioS – Integrative Bioinformatics and Systems Biology

iBioS is a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils, one of the founding directors of BioQuant, Heidelberg University's center for systems biology.

iBioS - short for integrative Bioinformatics and Systems Biology - works on the development of computer-assisted methods for the analysis of complex data generated in the modern life sciences and develops mathematical models for key cellular processes, for example in the context of virus infection or cancer. Theoretical projects are carried out in close collaboration with the experimental groups focusing on cellular death pathways.

Areas of major interest include:

Modeling and simulation of cellular systems
Data mining in molecular genetics and next generation sequencing
Data management for high-throughput technologies and medical samples
Quantitative monitoring of intra-cellular processes using light-microscopy
Biomedical computer vision

For more information on the research of iBioS go to Research Groups.

The multi-disciplinary team of iBioS consists of about 50 scientists from various fields including mathematics and physics, computer science, biology and medicine. The group members have published more than 200 papers in peer-reviewed journals since 2000.

The labs of the group are located in the DKFZ, at the IPMB and at the BioQuant at Heidelberg University. Members of iBioS have taken a leading role in several major initiatives in systems biology, most prominently ForSys and the Helmholtz Alliance on Systems Biology, both coordinated by Roland Eils.

iBioS at Group Retreat 2010 (click to magnify)

Newsflash

ICGC-Publication in Cell: PedBrain-Tumor consortium identifies linkage between p53 mutations and DNA-Rearrangements

The colloboration between the EMBL (Jan Korbel's group) and the DKFZ detected conspicous DNA rearrangement in several of the almost 100 sequenced tumor genomes from patients suffering from medulloblastoma, a very aggresive brain tumor found mainly in small children. Members of iBioS provided data management and bioinformatics expertise for this highly complex collaboration.

Roland Eils voted as Acting Director of BioQuant, Heidelberg University's Systems Biology Center

Recently, Roland Eils was voted Acting Director of BioQuant, Heidelberg University's Center for Quantitative Analysis of Molecular and Cellular Biosystems.

Radio-Feature on Total Genome Sequencing Projects in Heidelberg: All my Genes

On October 12, German radio station "SWR2" featured a full length radio show SWR2 Wissen on total genome projects with statements from Otmar D. Wiestler, Peter Lichter, Roland Eils and others.

ICSB 2011: Roland Eils chairs largest systems biology conference worldwide

The 12th International Conference on Systems Biology (ICSB 2012) took place from Aug. 28 to Sept 1, 2011 and attracted more than 1200 participants to the beautiful Rosengarten Conference Center in Mannheim. Congress president Roland Eils welcomed the participants who came to present and follow more than 100 individual talks and over 600 posters presenting cutting edge systems biology.