GROUP: Synthetic Biology

How do cells achieve the astonishing level of spatial organization that characterizes them? What are the mechanisms involved? We want to answer these questions using the bottom-up approach of synthetic biology, with a special focus on optogenetics.

 


Synthetic Biology

 

We are looking for a PhD Student. Please check the open positions.

 

In the Synthetic Biology group we are interested in understanding the molecular mechanisms that allow cells to organize their content in a highly complex spatiotemporal manner. In recent years, in fact, it has become more and more evident that even the small bacterial cells localize molecules – be it single proteins, macromolecular machineries or mRNAs – to specific addresses and that such localization is often under a tight temporal control. Therefore, spatiotemporal organization is an "ancient" cellular trait that adds to the other layers of regulation used by cells to control their processes.

 

   Synthetic networks for spatially confined cellular processes

  Using light to control the localization and function of proteins
  The Min system as a paradigm for self-organized pattern formation