Welcome to the eilslabs

The eilslabs form a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils.

 


 

2016-1 Steinhauser briefingsIn this recently published work, Sebastian Steinhauser and Nils Kurzawa have benchmarked 14 available tools to determine differential enrichment of transcription factor binding between two conditions. The work was part of the Master thesis of Sebastian Steinhauser, which he carried out in the eilslabs under the supervision of Carl Herrmann in the Cancer Regulatory Genomics group.
Their analysis highlights significant differences between the produced results and emphasizes the need for selective choice of the correct tool.

Read more here:
Steinhauser, S., Kurzawa, N., Eils, R., & Herrmann, C. (2016). A comprehensive comparison of tools for differential ChIP-seq analysis. Briefings in Bioinformatics. doi: 10.1093/bib/bbv110