Welcome to the eilslabs

The eilslabs form a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils.

 


Highlight Publications

For a full list of publications please use the links at the bottom!

  • Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm J, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R, Lehmann I (2016). Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Molecular Systems Biologyhttp://dx.doi.org/10.15252/msb.20156520
    Feed-IconRead the news feature:Maternal smoking is certainly harmful to the newborn child, but why?
  • Niopek, D., Wehler, P., Roensch, J., Eils, R., & Di Ventura, B. (2016). Optogenetic control of nuclear protein export. Nature Communications, 7, 10624. doi: 10.1038/ncomms10624
    Feed-IconRead the news feature: eilslabs Synthetic Biology team publishes second optogenetic tool in Nature Communications
  • Steinhauser, S., Kurzawa, N., Eils, R., & Herrmann, C. (2016). A comprehensive comparison of tools for differential ChIP-seq analysis. Briefings in Bioinformatics. doi: 10.1093/bib/bbv110
    Feed-IconRead the news feature: ChIP-seq analysis tools on the test - publication by two eilslabs' Master Students in Briefings in Bioinformatics
  • Alioto, T.S.*, Buchhalter, I.*, Derdak, S., Hutter, B., Eldridge, M.D., Hovig, E., Heisler, L.E., Beck, T.A., Simpson, J.T., Tonon, L., Sertier, A.S., Patch, A.M., Jager, N., Ginsbach, P., Drews, R., Paramasivam, N., Kabbe, R., Chotewutmontri, S., Diessl, N., Previti, C., Schmidt, S., Brors, B., Feuerbach, L., Heinold, M., Grobner, S., Korshunov, A., Tarpey, P.S., Butler, A.P., Hinton, J., Jones, D., Menzies, A., Raine, K., Shepherd, R., Stebbings, L., Teague, J.W., Ribeca, P., Giner, F.C., Beltran, S., Raineri, E., Dabad, M., Heath, S.C., Gut, M., Denroche, R.E., Harding, N.J., Yamaguchi, T.N., Fujimoto, A., Nakagawa, H., Quesada, V., Valdes-Mas, R., Nakken, S., Vodak, D., Bower, L., Lynch, A.G., Anderson, C.L., Waddell, N., Pearson, J.V., Grimmond, S.M., Peto, M., Spellman, P., He, M., Kandoth, C., Lee, S., Zhang, J., Letourneau, L., Ma, S., Seth, S., Torrents, D., Xi, L., Wheeler, D.A., Lopez-Otin, C., Campo, E., Campbell, P.J., Boutros, P.C., Puente, X.S., Gerhard, D.S., Pfister, S.M., McPherson, J.D., Hudson, T.J., Schlesner, M., Lichter, P., Eils, R.@, Jones, D.T. @, & Gut, I.G. @ (2015). A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing. Nature Communications, 6, 10001. doi: 10.1038/ncomms10001
    Feed-IconRead the news feature:  A new gold standard to improve cancer genome analysis
  • Schlesner, M., & Eils, R. (2015). Hypermutation takes the driver's seat. Genome Med, 7(1), 31. doi: 10.1186/s13073-015-0159-x
    Feed-IconRead the news feature: Research Highlight on Hypermutation in Cancer
  • Nolte, N., Kurzawa, N., Eils, R., & Herrmann, C. (2015). MapMyFlu: visualizing spatio-temporal relationships between related influenza sequences. Nucleic Acids Research. doi: 10.1093/nar/gkv417
    Feed-IconRead the news feature: MapMyFlu: visualizing influenza sequences based on geographical occurrence and dates
  • Evers, C., Paramasivam, N., Hinderhofer, K., Fischer, C., Granzow, M., Schmidt-Bacher, A., Eils, R., Steinbeisser, H., Schlesner, M., & Moog, U. (2015). SIPA1L3 identified by linkage analysis and whole-exome sequencing as a novel gene for autosomal recessive congenital cataract. Eur J Hum Genet. doi: 10.1038/ejhg.2015.46
  • Wegert, J.*, Ishaque, N. *, Vardapour, R., Geörg, C., Gu, Z., Bieg, M., Ziegler, B., Bausenwein, S., Nourkami, N., Ludwig, N., Keller, A., Grimm, C., Kneitz, S., Williams, Richard D., Chagtai, T., Pritchard-Jones, K., van Sluis, P., Volckmann, R., Koster, J., Versteeg, R., Acha, T., O’Sullivan, Maureen J., Bode, Peter K., Niggli, F., Tytgat, Godelieve A., van Tinteren, H., van den Heuvel-Eibrink, Marry M., Meese, E., Vokuhl, C., Leuschner, I., Graf, N., Eils, R., Pfister, Stefan M., Kool, M., & Gessler, M. (2015). Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors. CANCER CELL, 27(2), 298-311. doi: 10.1016/j.ccell.2015.01.002
    Feed-IconRead the news feature: Study Based on Whole Exome Sequencing Identifies New Genetic Causes For Wilms Tumors
  • Gu, L., Frommel, S.C., Oakes, C.C., Simon, R., Grupp, K., Gerig, C.Y., Bar, D., Robinson, M.D., Baer, C., Weiss, M., Gu, Z., Schapira, M., Kuner, R., Sultmann, H., Provenzano, M., Cancer, I.P.o.E.O.P., Yaspo, M.-L., Brors, B., Korbel, J., Schlomm, T., Sauter, G., Eils, R., Plass, C., & Santoro, R. (2014). BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence. Nature Genetics, advance online publication. doi: 10.1038/ng.3165

    Feed-Icon Read the news feature:  BAZ2A in prostate cancer

  • A new approach to study signaling rearrangements based on Fuzzy Logic (FL) that predicts changes in network architecture over time applied to melanoma:
    Bernardo-Faura, M., Massen, S., Falk, C.S., Brady, N.R., & Eils, R. (2014). Data-derived modeling characterizes plasticity of MAPK signaling in melanoma. PLoS Comput Biol, 10(9), e1003795. doi: 10.1371/journal.pcbi.1003795
  • New Publication in Cell Mechanics: Gladilin, E., Gonzalez, P., & Eils, R. (2014). Dissecting the contribution of actin and vimentin intermediate filaments to mechanical phenotype of suspended cells using high-throughput deformability measurements and computational modeling. J Biomech, 47(11), 2598-2605. doi: 10.1016/j.jbiomech.2014.05.020
  • Niopek, D., Benzinger, D., Roensch, J., Draebing, T., Wehler, P., Eils, R., & Di Ventura, B. (2014). Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells. Nature Communications, 5. doi: 10.1038/ncomms5404

    Feed-IconRead the news feature:  Directing the Cell by Light

  • Hovestadt, V., Jones, D.T., Picelli, S., Wang, W., Kool, M., Northcott, P.A., Sultan, M., Stachurski, K., Ryzhova, M., Warnatz, H.J., Ralser, M., Brun, S., Bunt, J., Jager, N., Kleinheinz, K., Erkek, S., Weber, U.D., Bartholomae, C.C., von Kalle, C., Lawerenz, C., Eils, J., Koster, J., Versteeg, R., Milde, T., Witt, O., Schmidt, S., Wolf, S., Pietsch, T., Rutkowski, S., Scheurlen, W., Taylor, M.D., Brors, B., Felsberg, J., Reifenberger, G., Borkhardt, A., Lehrach, H., Wechsler-Reya, R.J., Eils, R., Yaspo, M.L., Landgraf, P., Korshunov, A., Zapatka, M., Radlwimmer, B., Pfister, S.M., and Lichter, P. (2014). Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing. Nature. doi: 10.1038/nature13268
  • Martins, V.C., Busch, K., Juraeva, D., Blum, C., Ludwig, C., Rasche, V., Lasitschka, F., Mastitsky, S.E., Brors, B., Hielscher, T., Fehling, H.J., & Rodewald, H.-R. (2014). Cell competition is a tumour suppressor mechanism in the thymus. Nature, doi: 10.1038/nature13317
  • Kool, M., Jones, D.T., Jager, N., Northcott, P.A., Pugh, T.J., Hovestadt, V., Piro, R.M., Esparza, L.A., Markant, S.L., Remke, M., Milde, T., Bourdeaut, F., Ryzhova, M., Sturm, D., Pfaff, E., Stark, S., Hutter, S., Seker-Cin, H., Johann, P., Bender, S., Schmidt, C., Rausch, T., Shih, D., Reimand, J., Sieber, L., Wittmann, A., Linke, L., Witt, H., Weber, U.D., Zapatka, M., Konig, R., Beroukhim, R., Bergthold, G., van Sluis, P., Volckmann, R., Koster, J., Versteeg, R., Schmidt, S., Wolf, S., Lawerenz, C., Bartholomae, C.C., von Kalle, C., Unterberg, A., Herold-Mende, C., Hofer, S., Kulozik, A.E., von Deimling, A., Scheurlen, W., Felsberg, J., Reifenberger, G., Hasselblatt, M., Crawford, J.R., Grant, G.A., Jabado, N., Perry, A., Cowdrey, C., Croul, S., Zadeh, G., Korbel, J.O., Doz, F., Delattre, O., Bader, G.D., McCabe, M.G., Collins, V.P., Kieran, M.W., Cho, Y.J., Pomeroy, S.L., Witt, O., Brors, B., Taylor, M.D., Schuller, U., Korshunov, A., Eils, R., Wechsler-Reya, R.J., Lichter, P., Pfister, S.M., and Project, I.P.T. (2014). Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition. Cancer Cell 25, 393-405. doi: 10.1016/j.ccr.2014.02.004
  • Chenouard N, Smal I, de Chaumont F, Maška M, Sbalzarini IF, Gong Y, Cardinale J, Carthel C, Coraluppi S, Winter M, Cohen AR, Godinez WJ, Rohr K, Kalaidzidis Y, Liang L, Duncan J, Shen H, Xu Y, Magnusson KEG, Jaldén J, Blau HM, Paul-Gilloteaux P, Roudot P, Kervrann C, Waharte F, Tinevez J-Y, Shorte SL, Willemse J, Celler K, van Wezel GP, Dan H-W, Tsai Y-S, Ortiz de Solórzano C, Olivo-Marin J-C, Meijering E. Objective comparison of particle tracking methods. Nature Methods, March 2014, Volume 11, Issue 3, 281–289; DOI: 10.1038/nmeth.2808

    Feed-IconRead the news feature:  Excellent Result at Particle Tracking Challenge Published in Nature Methods

  • Kallenberger, S. M., Beaudouin, J., Claus, J., Fischer, C., Sorger, P. K., Legewie, S., & Eils, R. (2014). Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis. Sci. Signal., 7(316), ra23-. doi: 10.1126/scisignal.2004738

    Feed-IconRead the news feature: New eilslabs publication on regulation of apoptosis in Science Signaling highlighted by Science Editor

  • Beer, R., Herbst, K., Ignatiadis, N., Kats, I., Adlung, L., Meyer, H., . . . Di Ventura, B. (2014). Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange. MOLECULAR BIOSYSTEMS. doi: 10.1039/c3mb70594c

    Feed-IconRead the news feature:  iGEM Team Heidelberg 2013 publishes Grand-Prize project in Molecular Biosystems

  • Natalie Jäger , Matthias Schlesner, David T.W. Jones, Simon Raffel, Jan-Philipp Mallm, Kristin M. Junge, Dieter Weichenhan, Tobias Bauer, Naveed Ishaque, Marcel Kool, Paul A. Northcott, Andrey Korshunov, Ruben M. Drews, Jan Koster, Rogier Versteeg, Julia Richter, Michael Hummel, Stephen C. Mack, Michael D. Taylor, Hendrik Witt, Benedict Swartman, Dietrich Schulte-Bockholt, Marc Sultan, Marie-Laure Yaspo, Hans Lehrach, Barbara Hutter, Benedikt Brors, Stephan Wolf, Christoph Plass, Reiner Siebert, Andreas Trumpp, Karsten Rippe, Irina Lehmann, Peter Lichter, Stefan M. Pfister, Roland Eils: Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer, Cell, Available online 17 October 2013 http://dx.doi.org/10.1016/j.cell.2013.09.042

    Feed-IconRead the news feature: X-Chromosome Hypermutation: New Biological Phenomenon Discovered - Publication in Cell

  • Wang, Q., Gu, L., Adey, A., Radlwimmer, B., Wang, W., Hovestadt, V., Bähr, M., Wolf, S., Shendure, J., Eils, R., Plass, C., & Weichenhan, D. (2013). Tagmentation-based whole-genome bisulfite sequencing. Nat. Protocols, 8(10), 2022-2032. doi: 10.1038/nprot.2013.118

    Feed-IconRead the news feature: New publication in Nature Protocols: whole-genome bisulfite sequencing with minute amounts of DNA

  • Jones, D. T. W., Hutter, B., Jager, N., Korshunov, A., Kool, M., Warnatz, H.-J., . . . the International Cancer Genome Consortium PedBrain Tumor, P. (2013). Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics, advance online publication. doi: 10.1038/ng.2682

    Feed-IconRead the news feature: Pilocytic astrocytoma is predominantly a single-pathway disease

  • Moritz Aschoff, Agnes Hotz-Wagenblatt, Karl-Heinz Glatting, Matthias Fischer, Roland Eils and Rainer König SplicingCompass: differential splicing detection using RNA-Seq data. Bioinformatics 2013; doi: 10.1093/bioinformatics/btt101

    Feed-IconRead the news feature:SplicingCompass: differential splicing detection using RNA-Seq data

  • Joachim Weischenfeldt, Ronald Simon, Lars Feuerbach, Karin Schlangen, Dieter Weichenhan, Sarah Minner, Daniela Wuttig, Hans-Jörg Warnatz, Henning Stehr, Tobias Rausch, Natalie Jäger, Lei Gu, Olga Bogatyrova, Adrian M. Stütz, Rainer Claus, Jürgen Eils, Roland Eils, Clarissa Gerhäuser, Po-Hsien Huang, Barbara Hutter, Rolf Kabbe, Christian Lawerenz, Sylwester Radomski, Cynthia C. Bartholomae, Maria Fälth, Stephan Gade, Manfred Schmidt, Nina Amschler, Thomas Haß, Rami Galal, Jovisa Gjoni, Ruprecht Kuner, Constance Baer, Sawinee Masser, Christof von Kalle, Thomas Zichner, Vladimir Benes, Benjamin Raeder, Malte Mader, Vyacheslav Amstislavskiy, Meryem Avci, Hans Lehrach, Dmitri Parkhomchuk, Marc Sultan, Lia Burkhardt, Markus Graefen, Hartwig Huland, Martina Kluth, Antje Krohn, Hüseyin Sirma, Laura Stumm, Stefan Steurer, Katharina Grupp, Holger Sültmann, Guido Sauter, Christoph Plass, Benedikt Brors, Marie-Laure Yaspo, Jan O. Korbel, Thorsten Schlomm (2013). Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer. Cancer Cell, 23(2), 159–170. doi:10.1016/j.ccr.2013.01.002
    Feed-IconRead the news feature: Publication in Cancer Cell - Large Feedback in German Newspapers

  •  Beaudouin J, Liesche C, Aschenbrenner S, Hörner M and Eils R (2013) Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis. Cell Death and Differentiation advance online publication, 11 January 2013; doi:10.1038/cdd.2012.156
    Feed-IconRead the news feature: Changing the model of CD95 induced apoptosis with a new tool

  • Piro RM, Molineris I, Di Cunto F, Eils R, König R. Disease-gene discovery by integration of 3D gene expression and transcription factor binding affinities.Bioinformatics. 2013 [Epub ahead of print] doi: 10.1093/bioinformatics/bts720

  • Batra R, Harder N, Gogolin S, Diessl N, Soons Z, Jäger-Schmidt C,Lawerenz C, Eils R, Rohr K, Westermann F, König R. Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown, PLoS ONE (2012, in press).  http://dx.doi.org/10.1371/journal.pone.0050988

  • Goglin S, Batra  R, Harder N, Ehemann V, Paffhausen T , Diessl N, Gade S, Nolte I, Rohr K, König R, Westermann F. MYCN-mediated overexpression of mitotic spindle regulatory genes and loss of p53-p21 function jointly support the survival of tetraploid neuroblastoma cells, Cancer Letters (2012) http://dx.doi.org/10.1016/j.canlet.2012.11.028
    Feed-IconRead the news feature on the above: New Publications in PLoS One and Cancer Letters on Neuroblastoma

  • Richter, Julia, Matthias Schlesner, Steve Hoffmann, Markus Kreuz, Ellen Leich, Birgit Burkhardt, Maciej Rosolowski, et al. 2012. “Recurrent Mutation of the ID3 Gene in Burkitt Lymphoma Identified by Integrated Genome, Exome and Transcriptome Sequencing.” Nature Genetics advance on (November 11). DOI:  http://dx.doi.org/10.1038/ng.2469
    Feed-IconRead the news feature: Deciphering the genome of Burkitt-Lymphomas: Publication in Nature Genetics

  • Jones, David T W, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae Cho, et al. 2012. “Dissecting the Genomic Complexity Underlying Medulloblastoma.” Nature 488 (7409) (August 2): 100–5. DOI:  http://dx.doi.org/10.1038/nature11284
    Feed-IconRead the news feature: Nature Publication on Genomic Analysis of brain tumors

  • Rausch, Tobias, David T.W. Jones, Marc Zapatka, Adrian M. Stütz, Thomas Zichner, Joachim Weischenfeldt, Natalie Jäger, et al. 2012. “Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations.” Cell 148 (1-2) (January): 59–71. DOI: http://dx.doi.org/10.1016/j.cell.2011.12.013
  • Paulsen, Malte, Stefan Legewie, Roland Eils, Emil Karaulanov, and Christof Niehrs. 2011. “Negative Feedback in the Bone Morphogenetic Protein 4 (BMP4) Synexpression Group Governs Its Dynamic Signaling Range and Canalizes Development.” Proceedings of the National Academy of Sciences of the United States of America 108 (25) (June 21): 10202–7. DOI: http://dx.doi.org/10.1073/pnas.1100179108.
  • Mesecke, Sven, Doris Urlaub, Hauke Busch, Roland Eils, and Carsten Watzl. 2011. “Integration of Activating and Inhibitory Receptor Signaling by Regulated Phosphorylation of Vav1 in Immune Cells.” Science Signaling 4 (175) (January): ra36. DOI: http://dx.doi.org/10.1126/scisignal.2001325
  • Schramm, Gunnar, Stefan Wiesberg, Nicolle Diessl, Anna-Lena Kranz, Vitalia Sagulenko, Marcus Oswald, Gerhard Reinelt, Frank Westermann, Roland Eils, and Rainer König. 2010. “PathWave: Discovering Patterns of Differentially Regulated Enzymes in Metabolic Pathways.” Bioinformatics (Oxford, England) 26 (9) (May 1): 1225–31. DOI: http://dx.doi.org/10.1093/bioinformatics/btq113
  • Hamacher-Brady, Anne, Henning A Stein, Simon Turschner, Ina Toegel, Rodrigo Mora, Nina Jennewein, Thomas Efferth, Roland Eils, and Nathan R Brady. 2010. “Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalysed Lysosomal Reactive Oxygen Species Production.” The Journal of Biological Chemistry 286 (8) (December 13): 6587–601. DOI: http://dx.doi.org/10.1074/jbc.M110.210047
  • Neumann, Beate, Thomas Walter, Jean-Karim Hériché, Jutta Bulkescher, Holger Erfle, Christian Conrad, Phill Rogers, et al. 2010. “Phenotypic Profiling of the Human Genome by Time-lapse Microscopy Reveals Cell Division Genes.” Nature 464 (7289): 721–727. DOI: http://dx.doi.org/10.1038/nature08869
  • Neumann, Leo, Carina Pforr, Joel Beaudouin, Alexander Pappa, Nicolai Fricker, Peter H Krammer, Inna N Lavrik, and Roland Eils. 2010. “Dynamics Within the CD95 Death-inducing Signaling Complex Decide Life and Death of Cells.” Molecular Systems Biology 6 (352): 352. DOI: http://dx.doi.org/10.1038/msb.2010.6
  • Lewis, Nathan E, Gunnar Schramm, Aarash Bordbar, Jan Schellenberger, Michael P Andersen, Jeffrey K Cheng, Nilam Patel, et al. 2010. “Large-scale in Silico Modeling of Metabolic Interactions Between Cell Types in the Human Brain.” Nature Biotechnology 28 (12) (November 21): 1279–85. DOI: http://dx.doi.org/10.1038/nbt.1711
  • Busch, Hauke, David Camacho-Trullio, Zbigniew Rogon, Kai Breuhahn, Peter Angel, Roland Eils, and Axel Szabowski. 2008. “Gene Network Dynamics Controlling Keratinocyte Migration.” Molecular Systems Biology 4 (January): 199. DOI: http://dx.doi.org/10.1038/msb.2008.36
  • Conrad, Christian, Holger Erfle, Patrick Warnat, Nathalie Daigle, Thomas Lörch, Jan Ellenberg, Rainer Pepperkok, and Roland Eils. 2004. “Automatic Identification of Subcellular Phenotypes on Human Cell Arrays.” Genome Research 14 (6) (June): 1130–6. DOI: http://dx.doi.org/10.1101/gr.2383804 .
  • König, Rainer, and Roland Eils. 2004. “Gene Expression Analysis on Biochemical Networks Using the Potts Spin Model.” Bioinformatics (Oxford, England) 20 (10) (July 10): 1500–5. DOI: http://dx.doi.org/10.1093/bioinformatics/bth109

 Find Publications on PubMed:

Roland Eils Joel Beaudouin Benedikt Brors Christian Conrad Barbara Di Ventura
Jürgen Eils Evgeny Gladilin Rainer König Chris Lawerenz Karl Rohr
Matthias Schlesner
       

 


New eilslabs publication on regulation of apoptosis in Science Signaling highlighted by Science Editor

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    Created on March 18, 2014
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Kallenberger 2014

Our new publication on regulation of CD95-induced apoptosis via  caspase-8 self-cleavage was highlighted in the current Science issue by senior editor L. Bryan Ray. The article by Stefan Kallenberger et al. introduces a new modeling approach of simultaneously describing single cell and population data in a cell ensemble model. Using this approach, it was unravelled how the mechanisms of caspase-8 auto-cleavage, after activation of CD95 death receptors, ensures a precise control of apoptosis at various ligand concentrations.
Further Reading:

    Full article: Kallenberger, S.M., Beaudouin, J., Claus, J., Fischer, C., Sorger, P.K., Legewie, S., and Eils, R. (2014). Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis. Sci Signal 7, ra23-. doi: 10.1126/scisignal.2004738
        Full Text Access:
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    Science Editor's Choice: Ray, L.B. (2014). A Complicated Death. Science 343, 1178-c-1179. doi: 10.1126/science.343.6176.1178-c

iGEM Team Heidelberg 2013 publishes Grand-Prize project in Molecular Biosystems