Welcome to the eilslabs

The eilslabs form a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils.


  • Jabs, J., Zickgraf, F.M., Park, J., Wagner, S., Jiang, X., Jechow, K., Kleinheinz, K., Toprak, U.H., Schneider, M.A., Meister, M., Spaich, S., Sutterlin, M., Schlesner, M., Trumpp, A., Sprick, M., Eils, R., & Conrad, C. (2017). Screening drug effects in patient-derived cancer cells links organoid responses to genome alterations. Molecular Systems Biology, 13(11), 955. doi: 10.15252/msb.20177697
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  • Marin, R., Cortez, D., Lamanna, F., Pradeepa, M.M., Leushkin, E., Julien, P., Liechti, A., Halbert, J., Bruning, T., Mossinger, K., Trefzer, T., Conrad, C., Kerver, H.N., Wade, J., Tschopp, P., & Kaessmann, H. (2017). Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage. Genome Research, 27(12), 1974-1987. doi: 10.1101/gr.223727.117
  • Malte Wachsmuth*,Conrad, Christian*, Jutta Bulkescher, Birgit Koch, Robert Mahen, Mayumi Isokane, Rainer Peppekok, and Jan Ellenberg 2015. “High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cells." Nature Biotech 33, 384-389. DOI: http://dx.doi.org/10.1038/nbt.3146
  • Conrad, Christian, Annelie Wünsche, Tze Heng Tan, Jutta Bulkescher, Frank Sieckmann, Fatima Verissimo, Arthur Edelstein, et al. 2011. “Micropilot: Automation of Fluorescence Microscopy-based Imaging for Systems Biology.” Nature Methods 8 (3): 246–9. DOI: http://dx.doi.org/10.1038/nmeth.1558

Contribution screening microscopy:

  • Joana Almaça, Diana Faria, Marisa Sousa, Inna Uliyakina, Christian Conrad, Lalida Sirianant, et al. 2013. "High-Content siRNA Screen Reveals Global ENaC Regulators and Potential Cystic Fibrosis Therapy Targets." Cell 154 (6): 1390–1400. DOI: http://dx.doi.org/10.1016/j.cell.2013.08.045

  • James R A Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M Sykora, Martina Augsburg, et al. 2010. “Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins.” Science 328 (5978): 593–9. DOI: http://dx.doi.org/10.1126/science.1181348
  • Beate Neumann, Thomas Walter, Jean-Karim Hériché, Jutta Bulkescher, Holger Erfle, Christian Conrad, Phill Rogers, et al. 2010. “Phenotypic Profiling of the Human Genome by Time-lapse Microscopy Reveals Cell Division Genes.” Nature 464 (7289): 721–727. DOI: http://dx.doi.or/10.1038/nature08869

 Further Publications:

  • Christian Conrad, and Daniel W Gerlich. 2010. “Automated Microscopy for High-content RNAi Screening.” The Journal of Cell Biology 188 (4): 453–61. DOI: http://dx.doi.org/10.1083/jcb.200910105

  • Christian Conrad, Holger Erfle, Patrick Warnat, Nathalie Daigle, Thomas Lörch, Jan Ellenberg, Rainer Pepperkok, and Roland Eils. 2004. “Automatic Identification of Subcellular Phenotypes on Human Cell Arrays.” Genome Research 14 (6): 1130–6. DOI: http://dx.doi.org/10.1101/gr.2383804


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