GROUP: Theoretical Systems Biology

We are interested in cellular decision making by signal transduction networks and at the level of gene expression. We apply different theoretical methods ranging from ODE-based mechanistic modeling, over reverse engineering algorithms to agent-based modeling of cell population behaviour.


Theoretical Systems Biology

Head of eilslabs
Mathematikon - 02.MB.102
Berliner Str. 41
Im Neuenheimer Feld 267
D-69120 Heidelberg

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Phone: +49 6221/42 3600 (DKFZ) or /54 51290 (Uni)

Fax: +49 6221/42 3620 (DKFZ) or /54 51488 (Uni)


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Other information:



Division Head Theoretical Bioinformatics (B080 - DKFZ)

Ordinarius of Bioinformatics & Functional Genomics and Acting Director BIOQUANT, Heidelberg University



Diploma in Math and Informatics, RWTH Aachen, Germany


PhD in Mathematics and Computing, Heidelberg University     

Scientific Career


Guest Researcher at Université de Grenoble, France

1996 – 1999

Group Head, “Structure & Function in Cell Biology”, Heidelberg Univ.

Sincer 2002

Division Head "Theoretical Bioinformatics" (DKFZ)

Since 2004

Ordinarius of Bioinformatics & Functional Genomics, Heidelberg Univ.

Since 2009

Speaker of the Research Topic Functional Genomics, DKFZ

Since 2011

Acting Director Systems Biology Center BioQuant, Heidelberg Univ.

Since 2011

Co-Director of the Heidelberg Center for Personalized Oncology – DKFZ-HIPO



 Appointment for Program Director and Full Professor for Quantitative Biology at Cold Spring Harbor Laboratory, New York (declined)


Award for New Innovative Research by the Helmholtz Association “Systems Biology of Complex Diseases”


 Microsoft Research Award "Computational Tools for Advancing Science"


 BioFuture Prize from the German Ministry for Education and Research