Welcome to the eilslabs

The eilslabs form a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils.

 


The data in the publication demonstrates on the basis of whole genome sequencing of nearly 100 hundred pilocytic astrocytomas that observed mutations almost exclusively affect the MAPK pathway. The work is part of the ICGC PedBrain Project, which is coordinated by Peter Lichter and Roland Eils and the paper has two eilslabs members (Barbara Hutter and Natalie J├Ąger) as shared first authors together with David Jones from the Lichter lab.

The publication is online since July 2 at Nature Genetics:
Jones, D. T. W., Hutter, B., Jager, N., Korshunov, A., Kool, M., Warnatz, H.-J., . . . the International Cancer Genome Consortium PedBrain Tumor, P. (2013). Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nature Genetics, advance online publication. doi: 10.1038/ng.2682