Welcome to the eilslabs

The eilslabs form a joint research group between the division "Theoretical Bioinformatics" at the German Cancer Research Center (dkfz) and the department Bioinformatics and Functional Genomics at the Institute of Pharmacy and Molecular Biotechnology (IPMB) at Heidelberg University. The group is headed by Prof. Roland Eils.


The special issue on synthetic biology features many contributions from the international symposium “Synthetic Biology – from understanding to application”, which was hosted by the Helmholtz Initiative on Synthetic Biology at DKFZ in 2013. In their editorial “synthetic biology – ready for application”, the guest editors Roland Eils, Wolfgang Wiechert and Julia Ritzerfeld emphasize that there is already a lot of “synthetic biology inside” many biotechnology-oriented applications. Examples highlighted in this issue include streamlining the genomes of chassis organisms or constructing novel synthesis pathways. Further articles show the establishment of innovative genetic and molecular tools in microbial and mammalian synthetic biology. Three reviews summarize advances in mammalian optogenetics and synthetic viral delivery systems for genome editing, as well as recent advances in RNA aptamer development.