The Pan-Cancer Analysis of Whole Genomes (PCAWG) project brings together whole-genome sequencing data from the International Cancer Genome Consortium (ICGC) and The Cancer Genome Atlas (TCGA) projects, describing over 2000 tumour and matched control samples that cover more than 30 cancer entities.

The genomic data, over 1 Petabyte of data, are handled by seven academic computer centres worldwide, each holding a subset of the data. The DKFZ, together with the high-performance computing centres at the University of Chicago, the Electronics and Telecommunications Research Institute in Seoul, the University of California in Santa Cruz and the University of Tokyo serves as an academic community cloud provider, which enables researchers world-wide controlled access to this valuable data sets. Besides the provision of the necessary cloud infrastructure, the eilslabs, together with the Korbel group at EMBL, are also responsible for the development of one out of three computational pipelines to identify genetic variants on the individual subsets.



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